Description
| Product Name: | Human PMP2 Recombinant Protein |
| Product Code: | RPPB4264 |
| Size: | 25µg |
| Species: | Human |
| Target: | PMP2 |
| Synonyms: | P2, MP2, FABP8, M-FABP, Myelin P2 protein, PMP2, Peripheral Myelin Protein-2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The PMP2 protein solution contains 20mM Tris pH-7.5, 2mM EDTA, 1mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | MSNKFLGTWK LVSSENFDDY MKALGVGLAT RKLGNLAKPT VIISKKGDII TIRTESTFKN EISFKLGQE FEETTADNRK TKSIVTLQRG SLNQVQRWDG KETTIKRKLV NGKMVAECKM KGVVCTRIYE KV |
PMP2 is a small protein found in peripheral nerve myelin and spinal cord myelin, belongs to a family of fatty acid binding proteins. PMP2 partly decreases the inhibitory effect of T suppressors in the culture of immune lymph node cells. PMP2 protein is a lipid transport protein in schwann cells.
PMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids and having a molecular mass of 14.9 kDa.
| UniProt Protein Function: | PMP2: May play a role in lipid transport protein in Schwann cells. May bind cholesterol. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 8q21.3-q22.1 Cellular Component: cytoplasm; myelin sheath Molecular Function:cholesterol binding; fatty acid binding; protein binding; transporter activity Biological Process: transport |
| UniProt Code: | P02689 |
| NCBI GenInfo Identifier: | 4505909 |
| NCBI Gene ID: | 5375 |
| NCBI Accession: | NP_002668.1 |
| UniProt Secondary Accession: | P02689,Q6FHL4, |
| UniProt Related Accession: | P02689 |
| Molecular Weight: | 14,909 Da |
| NCBI Full Name: | myelin P2 protein |
| NCBI Synonym Full Names: | peripheral myelin protein 2 |
| NCBI Official Symbol: | PMP2�� |
| NCBI Official Synonym Symbols: | P2; MP2; FABP8; M-FABP�� |
| NCBI Protein Information: | myelin P2 protein |
| UniProt Protein Name: | Myelin P2 protein |
| UniProt Synonym Protein Names: | Peripheral myelin protein 2 |
| Protein Family: | Myelin P2 protein |
| UniProt Gene Name: | PMP2�� |
| UniProt Entry Name: | MYP2_HUMAN |