Human Plectin ELISA Kit

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SKU:
HUFI01471
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q15149
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
PLEC, Plectin, PCN, PLTN, Hemidesmosomal protein 1, HD1, Plectin-1, PLEC1, EBS1, EBSO, LGMD2Q, PLEC1b
Reactivity:
Human

Description

Human Plectin ELISA

Plectin is a structural protein, from the plakin protein family, that links different components of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only maintain cell and tissue integrity and orchestrate rapid changes in cytoarchitecture and cell shape but also act as scaffolding platforms for the assembly, positioning, and regulation of signalling complexes. Muscular dystrophy, limb-girdle and epidermolysis bullosa simplex 5A are all diseases linked to plectin. CDK-mediated phosphorylation and elimination of Cdc6 and cytoskeleton remodelling neurofilaments are two of its associated pathways.

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