Description
Product Name: | Human PLAC8 Recombinant Protein |
Product Code: | RPPB4257 |
Size: | 25µg |
Species: | Human |
Target: | PLAC8 |
Synonyms: | �Placenta-Specific 8, C15, Onzin, Placenta-Specific Gene 8 Protein, Protein C15. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile Filtered clear solution. |
Formulation: | PLAC8 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0),0.4M urea and 10% glycerol. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Purity: | Greater than 85.0% as determined by SDS-PAGE. |
Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMQAQAPV VVVTQPGVGP GPAPQNSNWQ TGMCDCFSDC GVCLCGTFCF PCLGCQVAAD MNECCLCGTS VAMRTLYRTR YGIPGSICDD YMATLCCPHC TLCQIKRDIN RRRAMRTF |
Placenta-Specific 8 (PLAC8) is a member of the cornifelin family. The PLAC8 protein is expressed at high levels in the plasmacytoid dendritic cells, spleen, lymph nodes, peripheral blood leukocytes, and bone marrow.
PLAC8 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 138 amino acids (1-115 a.a) and having a molecular mass of 14.9kDa.PLAC8 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
UniProt Protein Function: | PLAC8: Belongs to the cornifelin family.Chromosomal Location of Human Ortholog: 4q21.22Molecular Function: chromatin bindingBiological Process: brown fat cell differentiation; defense response to bacterium; negative regulation of apoptosis; negative regulation of multicellular organism growth; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; response to cold |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9NZF1 |
NCBI GenInfo Identifier: | 195222740 |
NCBI Gene ID: | 51316 |
NCBI Accession: | NP_001124188.1 |
UniProt Secondary Accession: | Q9NZF1,C1K3N2 |
UniProt Related Accession: | Q9NZF1 |
Molecular Weight: | |
NCBI Full Name: | placenta-specific gene 8 protein |
NCBI Synonym Full Names: | placenta specific 8 |
NCBI Official Symbol: | PLAC8�� |
NCBI Official Synonym Symbols: | C15; DGIC; onzin; PNAS-144�� |
NCBI Protein Information: | placenta-specific gene 8 protein |
UniProt Protein Name: | Placenta-specific gene 8 protein |
UniProt Synonym Protein Names: | Protein C15 |
Protein Family: | PLAC8-like protein |
UniProt Gene Name: | PLAC8�� |
UniProt Entry Name: | PLAC8_HUMAN |