Human PLA2G6 / IPLA2 ELISA Kit

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SKU:
HUFI00665
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O60733
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
85, 88 kDa calcium-independent phospholipase A2, EC:3.1.1.4, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-containing protein 9, PNPLA9
Reactivity:
Human
Research Area:
Cell Biology

Description

Human PLA2G6 / IPLA2 ELISA Kit

PLA2G6 (Phospholipase A2 Group VI) has been linked to Amyotrophic lateral sclerosis (ALS) a neurodegenerative disease. The protein encoded by PLA2G6 is a member of the phospholipase A2 family. It catalyzes the hydrolysis of membrane phospholipids, releasing arachidonic acid and lysophosphatidic acid. This enzyme is thought to play a role in innate immunity and inflammation. Mutations in the PLA2G6 gene have been found in about 5% of familial ALS cases and in about 1% of sporadic ALS cases.

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