Human PKC alpha / PRKCA ELISA Kit

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SKU:
HUFI01258
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P17252
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
PRKCA, Protein kinase C alpha type, PKCA, AAG6, PKC-A, PKC-alpha, PRKACA, aging-associated gene 6, protein kinase C, alpha
Reactivity:
Human
Research Area:
Cardiovascular

Description

Human PKC alpha / PRKCA ELISA Kit

Protein kinase C (PKC) is a group of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. Phorbol esters, a type of cancer promoter, bind to the PKC family members as major receptors. The protein produced by PKC alpha/PRKCA is one of the PKC family members, and each member of the family has a distinct expression profile. PKC alpha/PRKCA has been linked to a variety of cellular activities including cell adhesion, transformation, cell cycle checkpoints, and cell volume control. Knockout research in mice suggests that it may be a key regulator of cardiac contractility and Ca(2+) handling. Chordoid Glioma and Papillary Glioneuronal Tumors are two malignant tumors that can be caused by PRKCA.

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