Growth Factors & Cytokines Recombinant Proteins

Human PIP Protein Recombinant Protein (RPPB0886)

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SKU:
RPPB0886
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P12273
Research Area:
Growth Factors & Cytokines

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human PIP Protein Recombinant Protein
Product Code:RPPB0886
Size:20µg
Species:Human
Target:PIP Protein
Synonyms:Prolactin-inducible protein, Gross cystic disease fluid protein 15, GCDFP-15, Prolactin-induced protein, Secretory actin-binding protein, SABP, gp17, GCDFP15, GPIP4, PIP.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:PIP protein solution (1mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 10% glycerol and 0.4M Urea.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSQDNTRKI IIKNFDIPKS VRPNDEVTAV LAVQTELKEC MVVKTYLISS IPLQGAFNYK YTACLCDDNP KTFYWDFYTN RTVQIAAVVD VIRELGICPD DAAVIPIKNN RFYTIEILKV E

Prolactin-inducible protein (PIP) is a main protein component of benign breast gross cysts. PIP is a famous indicator of breast cancer, since it is found in around 50% of all breast cancer specimens. PIP is expressed in exocrine glands, in pathologic conditions, in breast cysts and breast cancers exhibiting apocrine features. PIP and prostate specific antigen are co-expressed in androgen receptor-positive breast tumours.

PIP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 141 amino acids (29-146 a.a.) and having a molecular mass of 15.9kDa.PIP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:PIP: Belongs to the PIP family.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Cytoskeletal; Secreted

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: extracellular region; extracellular space; nucleus

Molecular Function:aspartic-type endopeptidase activity; glycoprotein binding; IgG binding; protein binding; protein dimerization activity

Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste; proteolysis; retinal homeostasis; transmembrane transport

UniProt Code:P12273
NCBI GenInfo Identifier:134170
NCBI Gene ID:5304
NCBI Accession:P12273.1
UniProt Secondary Accession:P12273,A0A963, A0A9C3, A0A9F3, A4D2I1,
UniProt Related Accession:P12273
Molecular Weight:16,572 Da
NCBI Full Name:Prolactin-inducible protein
NCBI Synonym Full Names:prolactin induced protein
NCBI Official Symbol:PIP��
NCBI Official Synonym Symbols:GPIP4; GCDFP15; GCDFP-15��
NCBI Protein Information:prolactin-inducible protein
UniProt Protein Name:Prolactin-inducible protein
UniProt Synonym Protein Names:Gross cystic disease fluid protein 15; GCDFP-15; Prolactin-induced protein; Secretory actin-binding protein; SABP; gp17
Protein Family:Proline iminopeptidase
UniProt Gene Name:PIP��
UniProt Entry Name:PIP_HUMAN
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