Description
| Product Name: | Human PIH1D1 Recombinant Protein |
| Product Code: | RPPB4247 |
| Size: | 10µg |
| Species: | Human |
| Target: | PIH1D1 |
| Synonyms: | NOP17, NucleolarProtein 17 Homolog, PIH1 Domain-ContainingProtein 1, PIH1 Domain-Containing 1, PIH1D1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | PIH1D1 protein solution (0.25mg/ml) containing 20mMTris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greaterthan 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMANPKLL GMGLSEAEAI GADSARFEEL LLQASKELQQ AQTTRPESTQIQPQPGFCIK TNSSEGKVFI NICHSPSIPP PADVTEEELL QMLEEDQAGF RIPMSLGEPH AELDAKGQGCTAYDVAVNSD FYRRMQNSDF LRELVITIAR EGLEDKYNLQ LNPEWRMMKN RPFMGSISQQ NIRSEQRPRI QELGDLYTPA PGRAESGPEKPHLNLWLEAP DLLLAEVDLP KLDGALGLSL EIGENRLVMG GPQQLYHLDA YIPLQINSHE SKAAFHRKRKQLMVAMPLLP VPS |
PIH1 domain-containing protein 1 (PIH1D1) is a member of the PIH1family. PIH1D1 is a phylogenetically conserved protein vital for efficientprocessing of pre-rRNA through its association along with a class of smallnucleolar RNAs (snoRNAs) during ribosomal biogenesis. SnoRNAs are linked inribonucleoprotein particles localized to the nucleolus. PIH1D1 may also act asa novel modulator of apoptosis pathway.
PIH1D1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 313 amino acids (1-290a.a) andhaving a molecular mass of 34.8kDa. PIH1D1 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PIH1D1: a protein of unknown function. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 19q13.33 Cellular Component: cytoplasm; nucleolus; nucleus Molecular Function:ATPase binding; histone binding; phosphoprotein binding; protein binding; protein kinase binding Biological Process: box C/D snoRNP assembly; chromatin remodeling; epithelial cell differentiation; positive regulation of protein complex assembly; regulation of histone H3-K4 methylation; snoRNA localization |
| UniProt Code: | Q9NWS0 |
| NCBI GenInfo Identifier: | 74719379 |
| NCBI Gene ID: | 55011 |
| NCBI Accession: | Q9NWS0.1 |
| UniProt Secondary Accession: | Q9NWS0,Q9BVL0, B4DGN7, B4E2X7, |
| UniProt Related Accession: | Q9NWS0 |
| Molecular Weight: | 21,376 Da |
| NCBI Full Name: | PIH1 domain-containing protein 1 |
| NCBI Synonym Full Names: | PIH1 domain containing 1 |
| NCBI Official Symbol: | PIH1D1�� |
| NCBI Official Synonym Symbols: | NOP17�� |
| NCBI Protein Information: | PIH1 domain-containing protein 1 |
| UniProt Protein Name: | PIH1 domain-containing protein 1 |
| UniProt Synonym Protein Names: | Nucleolar protein 17 homolog |
| Protein Family: | PIH1 domain-containing protein |
| UniProt Gene Name: | PIH1D1�� |
| UniProt Entry Name: | PIHD1_HUMAN |
