Human PI3/Elafin Recombinant Protein (RPES2748)

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SKU:
RPES2748
Product Type:
Recombinant Protein
Species:
Human

Description

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Human PI3/Elafin Recombinant Protein

Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.

Product Name:Human PI3/Elafin Recombinant Protein (RPES2748)
Product Code:RPES2748
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Elafin, Elastase-Specific Inhibitor, ESI, Peptidase Inhibitor 3, PI-3, Protease inhibitor WAP3, Skin-Derived Antileukoproteinase, SKALP, WAP Four-Disulfide Core Domain Protein 14, PI3, WAP3, WFDC14
Accession:P19957
Sequence:Ala23-Gln117
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Elafin is produced by our Mammalian expression system and the target gene encoding Ala23-Gln117 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:11.0 kDa
AP Mol Mass:13-15 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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