Human PHF13 Recombinant Protein (RPPB4243)
- SKU:
- RPPB4243
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q86YI8
Description
| Product Name: | Human PHF13 Recombinant Protein |
| Product Code: | RPPB4243 |
| Size: | 5µg |
| Species: | Human |
| Target: | PHF13 |
| Synonyms: | PHF5, SPOC1, PHD finger protein 13, Survival time-associated PHD finger protein in ovarian cancer 1, PHF13. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The PHF13 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM DTT, 1mM EDTA and 250mM Imidazole. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMDSDSCA AAFHPEEYSP SCKRRRTVED FNKFCTFVLA YAGYIPYPKE ELPLRSSPSP ANSTAGTIDS DGWDAGFSDI ASSVPLPVSD RCFSHLQPTL LQRAKPSNFL LDRKKTDKLK KKKKRKRRDS DAPGKEGYRG GLLKLEAADP YVETPTSPTL QDIPQAPSDP CSGWDSDTPS SGSCATVSPD QVKEIKTEGK RTIVRQGKQV VFRDEDSTGN DEDIMVDSDD DSWDLVTCFC MKPFAGRPMI ECNECHTWIH LSCAKIRKSN VPEVFVCQKC RDSKFDIRRS NRSRTGSRKL FLD |
PHD finger protein 13 (PHF13) is necessary for normal chromosome separation during mitosis and also for normal chromosome condensation during the early stages of mitosis. PHF13 modulates chromatin structure.
PHF13 Human Recombinant produced in E. coli is a single polypeptide chain containing 323 amino acids (1-300) and having a molecular mass of 36kDa. PHF13 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PHF13: Modulates chromatin structure. Required for normal chromosome condensation during the early stages of mitosis. Required for normal chromosome separation during mitosis. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1p36.31 Cellular Component: nucleus Molecular Function:chromatin binding Biological Process: chromosome segregation; mitotic cell cycle; mitotic chromosome condensation |
| UniProt Code: | Q86YI8 |
| NCBI GenInfo Identifier: | 229462750 |
| NCBI Gene ID: | 148479 |
| NCBI Accession: | Q86YI8.2 |
| UniProt Secondary Accession: | Q86YI8,Q59FB6, Q5TH65, Q8N551, Q9UJP2, B3KUQ7, |
| UniProt Related Accession: | Q86YI8 |
| Molecular Weight: | 33,582 Da |
| NCBI Full Name: | PHD finger protein 13 |
| NCBI Synonym Full Names: | PHD finger protein 13 |
| NCBI Official Symbol: | PHF13�� |
| NCBI Official Synonym Symbols: | PHF5; SPOC1�� |
| NCBI Protein Information: | PHD finger protein 13 |
| UniProt Protein Name: | PHD finger protein 13 |
| UniProt Synonym Protein Names: | Survival time-associated PHD finger protein in ovarian cancer 1; SPOC1 |
| Protein Family: | PHD finger protein |
| UniProt Gene Name: | PHF13�� |
| UniProt Entry Name: | PHF13_HUMAN |
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