Description
system_update_altDatasheet
Human PGD Recombinant Protein
6-phosphogluconate dehydrogenase(PGD) is a cytoplasm-located protein; and belongs to the 6-phosphogluconate dehydrogenase family. 6PGD is the second dehydrogenase in the pentose phosphate shunt. It catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2; with concomitant reduction of NADP to NADPH. Mutations within the gene coding this enzyme result in 6-phosphogluconate dehydrogenase deficiency; an autosomal hereditary disease effecting the red blood cells.
| Product Name: | Human PGD Recombinant Protein (RPES4005) |
| Product Code: | RPES4005 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | 6-phosphogluconate dehydrogenase, Decarboxylating,PGD,PGDH,6PGD |
| Accession: | P52209 |
| Sequence: | Met 1-Ala483 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human 6-phosphogluconate dehydrogenase is produced by our Mammalian expression system and the target gene encoding Met1-Ala483 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 54.2 kDa |
| AP Mol Mass: | 58 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM PB;150mM NaCl;pH7.4. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Metabolism |