Metabolism Recombinant Proteins
Human PFK1/PFKM Recombinant Protein (RPES2459)
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- SKU:
- RPES2459
Description
system_update_altDatasheet
Human PFK1/PFKM Recombinant Protein
PFK1, also known as PFKM, is a regulatory glycolytic enzyme. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. It is a muscle-type isozyme. There are three phosphofructokinase isozymes in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Mutations in PFK1 gene have been related with glycogen storage disease type VII, also identified as Tarui disease.
| Product Name: | Human PFK1/PFKM Recombinant Protein (RPES2459) |
| Product Code: | RPES2459 |
| Size: | 50µg |
| Species: | Human |
| Expressed Host: | Baculovirus-Insect Cells |
| Synonyms: | 6-phosphofructokinase, muscle type,Phosphofructo-1-kinase isozyme A,Phosphofructokinase 1,Phosphohexokinase,PFKM,PFKX,ATP-PFK,GSD7,PFK-1,PFK1,PFKA,PPP1R122 |
| Accession: | P08237-1 |
| Sequence: | Thr 2-Val 780 |
| Fusion tag: | N-His & GST |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human PFKM (P08237-1) (Thr2-Val780) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 112.9 kDa |
| AP Mol Mass: | 113 kDa |
| Formulation: | Supplied as sterile 20mM Tris, 500mM NaCl, pH 8.5, 10% glycerol |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Metabolism |
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