Cell Death Recombinant Proteins

Human PDCD4/H731 Recombinant Protein (RPES1408)

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SKU:
RPES1408
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Death

Description

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Human PDCD4/H731 Recombinant Protein

Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.

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