Human PDCD1LG2 Recombinant Protein (RPPB4207)
- SKU:
- RPPB4207
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BQ51
Description
| Product Name: | Human PDCD1LG2 Recombinant Protein |
| Product Code: | RPPB4207 |
| Size: | 25µg |
| Species: | Human |
| Target: | PDCD1LG2 |
| Synonyms: | Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, PDCD1LG2, B7-DC, Butyrophilin B7-DC, CD273, B7DC, CD273, PDCD1L2, PDL2, bA574F11.2, Btdc. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | PDCD1LG2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSLFTVTVP KELYIIEHGS NVTLECNFDT GSHVNLGAIT ASLQKVENDT SPHRERATLL EEQLPLGKAS FHIPQVQVRD EGQYQCIIIY GVAWDYKYLT LKVKASYRKI NTHILKVPET DEVELTCQAT GYPLAEVSWP NVSVPANTSH SRTPEGLYQV TSVLRLKPPP GRNFSCVFWN THVR |
Programmed cell death 1 ligand 2 (PDCD1LG2) which takes part in the costimulatory signal, is necessary for T-cell proliferation. PDCD1LG2 is also involved in IFNG production in a PDCD1-independent way. The interaction with PDCD1 inhibits T-cell proliferation by preventing cytokine production and cell cycle progression.
PDCD1LG2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 204 amino acids (20-200 a.a.) and having a molecular mass of 22.8kDa.PDCD1LG2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. |
| UniProt Code: | Q9BQ51 |
| NCBI GenInfo Identifier: | 73917618 |
| NCBI Gene ID: | 80380 |
| NCBI Accession: | Q9BQ51.2 |
| UniProt Secondary Accession: | Q9BQ51,Q14CN8, Q5T7Z6, Q6JXL8, Q6JXL9, |
| UniProt Related Accession: | Q9BQ51 |
| Molecular Weight: | 20,745 Da |
| NCBI Full Name: | Programmed cell death 1 ligand 2 |
| NCBI Synonym Full Names: | programmed cell death 1 ligand 2 |
| NCBI Official Symbol: | PDCD1LG2�� |
| NCBI Official Synonym Symbols: | B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2�� |
| NCBI Protein Information: | programmed cell death 1 ligand 2 |
| UniProt Protein Name: | Programmed cell death 1 ligand 2 |
| UniProt Synonym Protein Names: | Butyrophilin B7-DC; B7-DC; CD_antigen: CD273 |
| Protein Family: | Programmed cell death |
| UniProt Gene Name: | PDCD1LG2�� |
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