Immunology Recombinant Proteins

Human PD-L2/CD273 Recombinant Protein (RPES0344)

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RPES0344

Description

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Human PD-L2/CD273 Recombinant Protein

Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart; placenta; pancreas; lung and liver; it is weakly expressed in the spleen; lymph nodes; and thymus. PDCD1LG2 is involved in the costimulatory signal; essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

Product Name:Human PD-L2/CD273 Recombinant Protein (RPES0344)
Product Code:RPES0344
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Programmed Cell Death 1 Ligand 2, PD-1 Ligand 2, PD-L2, PDCD1 Ligand 2, Programmed Death Ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2
Accession:Q9BQ51
Sequence:Leu20-Pro219
Fusion tag:C-mFc
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human PD-L2 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro219 is expressed with a mFc tag at the C-terminus.
Purity:> 95% as determined by reducing SDS-PAGE.
Mol Mass:49.2 kDa
AP Mol Mass:60-90 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology
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