Immunology Recombinant Proteins
Human PD-L2/CD273 Recombinant Protein (RPES0344)
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- SKU:
- RPES0344
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immunology
Description
system_update_altDatasheet
Human PD-L2/CD273 Recombinant Protein
Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart; placenta; pancreas; lung and liver; it is weakly expressed in the spleen; lymph nodes; and thymus. PDCD1LG2 is involved in the costimulatory signal; essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
| Product Name: | Human PD-L2/CD273 Recombinant Protein (RPES0344) |
| Product Code: | RPES0344 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Programmed Cell Death 1 Ligand 2, PD-1 Ligand 2, PD-L2, PDCD1 Ligand 2, Programmed Death Ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2 |
| Accession: | Q9BQ51 |
| Sequence: | Leu20-Pro219 |
| Fusion tag: | C-mFc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human PD-L2 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro219 is expressed with a mFc tag at the C-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 49.2 kDa |
| AP Mol Mass: | 60-90 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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