Immune Checkpoint Recombinant Proteins
Human PD-1 Recombinant Protein (mFc-His Tag) (HDPT0025)
- SKU:
- HDPT0025
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human PD-1 Recombinant Protein (mFc-His Tag)
Description: | This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
Product name: | Human PD-1 Recombinant Protein (mFc-His Tag) |
Synonyms: | PDCD1, PD1, CD279, SLEB2 |
Type: | protein |
Size: | 50 µg |
Name: | PD-1 |
Origin: | Human |
Source: | HEK293 |
Protein Type: | Recombinant |
Application: | ELISA |
Purity: | > 95% |
Purification: | affinity purification |
Format: | Lyophilized |
Conjugate: | C-Mouse Fc and 6×His tag |
Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
Usage: | Research use only |
Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
Reconstitution: | Reconstitute with deionized water |
Sequence: | PD-1(Phe24-Val170)+mFc(Pro99-Lys330)+6×His tag |
Gene ID: | 5133 |
Uniprot: | Q15116 |
Molecular Weight: | 43.5 kDa |