Enzymes Recombinant Proteins

Human PCYT2 Recombinant Protein (RPPB2077)

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SKU:
RPPB2077
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q99447
Research Area:
Enzymes

Description

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Product Name:Human PCYT2 Recombinant Protein
Product Code:RPPB2077
Size:5µg
Species:Human
Target:PCYT2
Synonyms:MEA-phosphate cytidylyltransferase, CTP:phospho MEA cytidylyltransferase, Phosphoryl MEA transferase, PCYT2, ET.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The PCYT2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl, 1mM DTT and 0.1mM PMSF.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MIRNGRGAAG GAEQPGPGGR RAVRVWCDGC YDMVHYGHSN QLRQARAMGD YLIVGVHTDE EIAKHKGPPV FTQEERYKMV QAIKWVDEVV PAAPYVTTLE TLDKYNCDFC VHGNDITLTV DGRDTYEEVK QAGRYRECKR TQGVSTTDLV GRMLLVTKAH HSSQEMSSEY REYADSFGKC PGGRNPWTGV SQFLQTSQKI IQFASGKEPQ PGETVIYVAG AFDLFHIGHV DFLEKVHRLA ERPYIIAGLH FDQEVNHYKG KNYPIMNLHE RTLSVLACRY VSEVVIGAPY AVTAELLSHF KVDLVCHGKT EIIPDRDGSD PYQEPKRRGI FRQIDSGSNL TTDLIVQRII TNRLEYEARN QKKEAKELAF LEAARQQAAQ PLGERDGDF

PCYT2 is a member of the cytidylyltransferase family. PCYT2 is an enzyme which catalyzes the formation of CDP-MEA from CTP and phospho MEA in the Kennedy pathway of phospholipid synthesis. PCYT2 has the strongest expression in the liver, heart, and skeletal muscle.

PCYT2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 409 amino acids (1-389) and having a molecular mass of 45.9kDa.PCYT2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine.
NCBI Summary:This gene encodes an enzyme that catalyzes the formation of CDP-ethanolamine from CTP and phosphoethanolamine in the Kennedy pathway of phospholipid synthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
UniProt Code:Q99447
NCBI GenInfo Identifier:14603223
NCBI Gene ID:5833
NCBI Accession:AAH10075.1
UniProt Secondary Accession:Q99447,Q6IBM3, Q96G08, B7Z7A5, B7ZAS0, F5H8B1,
UniProt Related Accession:Q99447
Molecular Weight:35,200 Da
NCBI Full Name:Phosphate cytidylyltransferase 2, ethanolamine
NCBI Synonym Full Names:phosphate cytidylyltransferase 2, ethanolamine
NCBI Official Symbol:PCYT2��
NCBI Official Synonym Symbols:ET��
NCBI Protein Information:ethanolamine-phosphate cytidylyltransferase
UniProt Protein Name:Ethanolamine-phosphate cytidylyltransferase
UniProt Synonym Protein Names:CTP:phosphoethanolamine cytidylyltransferase; Phosphorylethanolamine transferase
UniProt Gene Name:PCYT2��
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