Human PBLD Recombinant Protein (RPPB4192)
- SKU:
- RPPB4192
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P30039
Description
| Product Name: | Human PBLD Recombinant Protein |
| Product Code: | RPPB4192 |
| Size: | 20µg |
| Species: | Human |
| Target: | PBLD |
| Synonyms: | Phenazine biosynthesis-like domain-containing protein, MAWD-binding protein, Unknown protein 32 from 2D-page of liver tissue, PBLD, MAWBP, MAWDBP, FLJ14767, FLJ35507. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The PBLD solution (1 mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 10% glycerol, 2mM DTT and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MKLPIFIADA FTARAFRGNP AAVCLLENEL DEDMHQKIAR EMNLSETAFI RKLHPTDNFA QSSCFGLRWF TPASEVPLCG HATLASAAVL FHKIKNMNST LTFVTLSGEL RARRAEDGIV LDLPLYPAHP QDFHEVEDLI KTAIGNTLVQ DICYSPDTQK LLVRLSDVYN RSFLENLKVN TENLLQVENT GKVKGLILTL KGEPGGQTQA FDFYSRYFAP WVGVAEDPVT GSAHAVLSSY WSQHLGKKEM HAFQCSHRGG ELGISLRPDG RVDIRGGAAV VLEGTLTA |
PBLD is member of the phenazine biosynthesis-like protein (PhzF) family. PBLD which is expressed in most tissues is the only representative of the PhzF family in the human genome. PBLD participates in the MAPK signaling pathway. PBLD is involved in multiple basic cellular functions, its expression is elevated in several disease processes, including folate deficiency and hypotension.
PBLD Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 308 amino acids (1-288 a.a.) and having a molecular mass of 33.9kDa. The PBLD is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PBLD: Belongs to the PhzF family.Protein type: Isomerase; EC 5.1.-.-Chromosomal Location of Human Ortholog: 10q21.3Cellular Component: cytoplasmMolecular Function: protein bindingBiological Process: maintenance of gastrointestinal epithelium; negative regulation of epithelial cell proliferation; negative regulation of transforming growth factor beta receptor signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P30039 |
| NCBI GenInfo Identifier: | 17380331 |
| NCBI Gene ID: | 64081 |
| NCBI Accession: | P30039.2 |
| UniProt Secondary Accession: | P30039,Q9HCC2, A8MZJ3, C9JIM0 |
| UniProt Related Accession: | P30039 |
| Molecular Weight: | 31,409 Da |
| NCBI Full Name: | Phenazine biosynthesis-like domain-containing protein |
| NCBI Synonym Full Names: | phenazine biosynthesis like protein domain containing |
| NCBI Official Symbol: | PBLD�� |
| NCBI Official Synonym Symbols: | MAWBP; MAWDBP; HEL-S-306�� |
| NCBI Protein Information: | phenazine biosynthesis-like domain-containing protein |
| UniProt Protein Name: | Phenazine biosynthesis-like domain-containing protein |
| UniProt Synonym Protein Names: | MAWD-binding protein; MAWDBP; Unknown protein 32 from 2D-page of liver tissue |
| Protein Family: | Phenazine biosynthesis-like domain-containing protein |
| UniProt Gene Name: | PBLD�� |
| UniProt Entry Name: | PBLD_HUMAN |
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