Human PBEF/NAMPT Recombinant Protein (His Tag)
- SKU:
- RPES5279
Description
| Product Name: | Human PBEF/NAMPT Recombinant Protein (His Tag) |
| Product Code: | RPES5279 |
| Size: | 20µg |
| Species: | Human |
| Expression Host: | E.coli |
| Synonyms: | Pre-B cell-enhancing factor, Nicotinamide phosphoribosyltransferase, NAmPRTase, Nampt, Pre-B-cell colony-enhancing factor 1, Visfatin, NAMPT, PBEF, PBEF1 |
| Mol Mass: | 57 kDa |
| AP Mol Mass: | 55 kDa |
| Tag: | N-His |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Bio Activity: | Testing in progress |
| Sequence: | Met1-His491 |
| Accession: | P43490 |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation: | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed man |
| Reconstitution: | Please refer to the printed manual for detailed information. |
| Background: | Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells; but it is also acknowledged to be the ubiquitous intracellular enzyme nicotinamide phosphoribosyltranferase (NAMPT) and the adipokine “visfatin”. PBEF is constitutively expressed in the fetal membranes where its greatest expression is in the amnion. It has intracellular and extracellular forms. Most of the intracellular functions of PBEF are due to its role as a Nampt which can induce angiogenesis through upregulation of VEGF and VEGFR and secretion of MCP-1. Extracellular PBEF has been shown to increase inflammatory cytokines; such as TNF-α; IL-1β; IL-16; and TGF-β1. PBEF also increases the production of IL-6; TNF-α; and IL-1β in CD14+ monocyctes; macrophages; and dendritic cells; enhances the effectiveness of T cells. |
Related Products
Rat NAMPT/PBEF Recombinant Protein (His tag)
OverviewProduct Name:Rat NAMPT/PBEF Recombinant Protein (His tag)Product Code:RPES5865Size:20µgSpecies:RatExpre
Human PBEF/NAMPT Recombinant Protein (RPES0421)
Cell Biology Recombinant Proteins
system_update_altDatasheetHuman PBEF/NAMPT Recombinant Protein Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differen
Human PBEF/NAMPT Recombinant Protein (RPES0932)
Growth Factors & Cytokines Recombinant Proteins
system_update_altDatasheetHuman PBEF/NAMPT Recombinant Protein Nicotinamide phosphoribosyltransferase (NAMPT); also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin; is an enzyme
Human IL10 Recombinant Protein (His tag)
OverviewProduct Name:Human IL10 Recombinant Protein (His tag)Product Code:RPES5478Size:20µgSpecies:HumanExpress
Human G6PD Recombinant Protein (His tag)
OverviewProduct Name:Human G6PD Recombinant Protein (His tag)Product Code:RPES5421Size:20µgSpecies:HumanExpress