Human PACT Recombinant Protein (His tag)

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SKU:
RPES5627
Product Type:
Recombinant Protein
Species:
Human

Description

Product Name:Human PACT Recombinant Protein (His tag)
Product Code:RPES5627
Size:20µg
Species:Human
Expression Host:E.coli
Synonyms:Interferon-inducible double-stranded RNA-dependent protein kinase activator A, PRKRA, PKR-associated protein X
Mol Mass:34.32 kDa
AP Mol Mass:38 kDa
Tag:N-His & C-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Met 1-Lys 313
Accession:O75569
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Activates EIF2AK2/PKR in the absence of double stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1.
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