Human P2RX7 Full-Length Bioactive Membrane Protein (HDFP030)

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SKU:
HDFP030
Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
Q99572

Description

system_update_altDatasheet
Product nameHuman P2RX7 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP030
Product CategoryFull Length Transmembrane Proteins
Target:P2RX7
Uniprot:Q99572
Description:Human P2RX7 full length protein-synthetic nanodisc
Molecular Weight:The human full length P2RX7 protein has a MW of 68.4 kDa
Protein Family:Druggable Genome, Ion Channels: ATP Receptors, Transmembrane
Protein Pathways:Calcium signaling pathway, Neuroactive ligand-receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:P2X7
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
Delivery:3-4 weeks
UsageResearch use only
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