Immune Checkpoint Recombinant Proteins

Human OX40 Recombinant Protein (hFc-His Tag) (HDPT0022)

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SKU:
HDPT0022
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human OX40 Recombinant Protein (hFc-His Tag)

Description:The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Product name:Human OX40 Recombinant Protein (hFc-His Tag)
Synonyms:TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L
Type:protein
Size:50 µg
Name:OX40
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Flow Cyt
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc and 6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:OX40(Leu29-Ala216)+hFc(Glu99-Ala330)+6×His tag
Gene ID:7293
Uniprot:P43489
Molecular Weight:47.2 kDa
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