Immune Checkpoint Recombinant Proteins
Human OX40 Recombinant Protein (hFc-His Tag) (HDPT0022)
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- SKU:
- HDPT0022
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human OX40 Recombinant Protein (hFc-His Tag)
| Description: | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
| Product name: | Human OX40 Recombinant Protein (hFc-His Tag) |
| Synonyms: | TNFRSF4, OX40, CD134, OX40L receptor, ACT35, TXGP1L |
| Type: | protein |
| Size: | 50 µg |
| Name: | OX40 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Flow Cyt |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc and 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | OX40（Leu29-Ala216）+hFc（Glu99-Ala330）+6×His tag |
| Gene ID: | 7293 |
| Uniprot: | P43489 |
| Molecular Weight: | 47.2 kDa |
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