Human ORM2 Recombinant Protein (RPPB4167)
- SKU:
- RPPB4167
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P19652
Description
| Product Name: | Human ORM2 Recombinant Protein |
| Product Code: | RPPB4167 |
| Size: | 20µg |
| Species: | Human |
| Target: | ORM2 |
| Synonyms: | Orosomucoid 2, Alpha-1-Acid Glycoprotein Type 2, OMD 2, AGP2, AGP-B, Type 2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The ORM2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMQIPLC ANLVPVPITN ATLDRITGKW FYIASAFRNE EYNKSVQEIQ ATFFYFTPNK TEDTIFLREY QTRQNQCFYN SSYLNVQREN GTVSRYEGGR EHVAHLLFLR DTKTLMFGSY LDDEKNWGLS FYADKPETTK EQLGEFYEAL DCLCIPRSDV MYTDWKKDKC EPLEKQHEKE RKQEEGES |
ORM2 is a significant acute phase plasma protein. ORM2 is highly expressed as a result of acute inflammation there for it is categorized as an acute-phase reactant.
ORM2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 208 amino acids (19-201) and having a molecular mass of 24.3kDa.ORM2 is fused to a 25 amino acid His-tag at N-terminus.
| UniProt Protein Function: | ORM2: Functions as transport protein in the blood stream. Binds various hydrophobic ligands in the interior of its beta- barrel domain. Also binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction. Belongs to the calycin superfamily. Lipocalin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 9q32 Cellular Component: extracellular space Biological Process: regulation of immune system process; transport; acute-phase response |
| NCBI Summary: | This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P19652 |
| NCBI GenInfo Identifier: | 231458 |
| NCBI Gene ID: | 5005 |
| NCBI Accession: | P19652.2 |
| UniProt Secondary Accession: | P19652,Q16571, Q5T538, Q6IB74, B2R5L2, |
| UniProt Related Accession: | P19652 |
| Molecular Weight: | 23,603 Da |
| NCBI Full Name: | Alpha-1-acid glycoprotein 2 |
| NCBI Synonym Full Names: | orosomucoid 2 |
| NCBI Official Symbol: | ORM2�� |
| NCBI Official Synonym Symbols: | AGP2; AGP-B; AGP-B'�� |
| NCBI Protein Information: | alpha-1-acid glycoprotein 2; AGP 2; OMD 2; orosomucoid-2; alpha-1-acid glycoprotein, type 2 |
| UniProt Protein Name: | Alpha-1-acid glycoprotein 2 |
| UniProt Synonym Protein Names: | Orosomucoid-2 |
| Protein Family: | Alpha-1-acid glycoprotein |
| UniProt Gene Name: | ORM2�� |
| UniProt Entry Name: | A1AG2_HUMAN |
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