Human OMP Recombinant Protein (RPPB4158)

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SKU:
RPPB4158
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P47874

Description

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Product Name:Human OMP Recombinant Protein
Product Code:RPPB4158
Size:20µg
Species:Human
Target:OMP
Synonyms:Olfactory neuronal-specific protein, Olfactory marker protein, OMP.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:OMP protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAEDRPQ QPQLDMPLVL DQGLTRQMRL RVESLKQRGE KRQDGEKLLQ PAESVYRLNF TQQQRLQFER WNVVLDKPGK VTITGTSQNW TPDLTNLMTR QLLDPTAIFW RKEDSDAIDW NEADALEFGE RLSDLAKIRK VMYFLVTFGE GVEPANLKAS VVFNQL

Olfactory marker protein (OMP) which is expressed in the cytoplasm of olfactory chemosensory neurons in the nasal neuroepithelium, is associated in a unique way with the mature olfactory receptor neurons in numerous vertebrate species. OMP have a modulatory part in the odor detection/signal transduction cascade ant its expression is a sign of mature vertebrate olfactory receptor neurons (ORNs). OMP is also a potent enhancer of mitosis in fetal olfactory epithelial cells and it promotes an increase in uptake of tritiated thymidine in liver.

OMP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 186 amino acids (1-163 a.a) and having a molecular mass of 21.3kDa. OMP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:OMP: May act as a modulator of the olfactory signal- transduction cascade. Belongs to the olfactory marker protein family.Chromosomal Location of Human Ortholog: 11q13.5Cellular Component: axon; cell soma; cytosol; nucleusMolecular Function: signal transducer activityBiological Process: synaptic transmission
UniProt Protein Details:
NCBI Summary:Olfactory marker protein is uniquely associated with the mature olfactory receptor neurons in many vertebrate species from fish to man. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Results of the mouse knockout studies show that OMP-null mice are compromised in their ability to respond to odor stimuli, and that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. [provided by RefSeq, Jul 2008]
UniProt Code:P47874
NCBI GenInfo Identifier:1352639
NCBI Gene ID:4975
NCBI Accession:P47874.2
UniProt Secondary Accession:P47874,Q562G2
UniProt Related Accession:P47874
Molecular Weight:18,937 Da
NCBI Full Name:Olfactory marker protein
NCBI Synonym Full Names:olfactory marker protein
NCBI Official Symbol:OMP��
NCBI Official Synonym Symbols:
NCBI Protein Information:olfactory marker protein
UniProt Protein Name:Olfactory marker protein
UniProt Synonym Protein Names:Olfactory neuronal-specific protein
Protein Family:OmpA-like protein
UniProt Gene Name:OMP��
UniProt Entry Name:OMP_HUMAN
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