Human NXT2 Recombinant Protein (RPPB4148)
- SKU:
- RPPB4148
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NPJ8
Description
| Product Name: | Human NXT2 Recombinant Protein |
| Product Code: | RPPB4148 |
| Size: | 25µg |
| Species: | Human |
| Target: | NXT2 |
| Synonyms: | NTF2-related export protein 2, Protein p15-2, NXT2, BM-025, DC9, P15-2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | NXT2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 40% glycerol and 200mM NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMRKYRS HWSQGDREGY QRRSNYYEGP HTSHSSPADR TREEVVTPTL PEHTATRSQM ATSLDFKTYV DQACRAAEEF VNIYYETMDK RRRALTRLYL DKATLIWNGN AVSGLDALNN FFDTLPSSEF QVNMLDCQPV HEQATQSQTT VLVVTSGTVKFDGNKQHFFN QNFLLTAQST PNNTVWKIAS DCFRFQDWSS S |
Nuclear transport factor 2-like export factor 2 (NXT2) belongs to the NXT family proteins which are commonly involved in exporting nuclear RNA in eukaryotic cells. The NXT2 protein is a regulator of protein export for NES-containing proteins. In addition, NXT2 associates with NXF1, NXF2, NXF3 and NXF5 and has a role in mRNA nuclear export. NXT2 has a critical role in upholding morphogenetic integrity of embryonic heart in vertebrate species. The NXT2 protein contains a nuclear transport factor 2 (NTF2) domain, which has a vital role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus, it may also have a role in mRNA nuclear export.
NXT2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 221 amino acids (1-197 a.a) and having a molecular mass of 25.3kDa.NXT2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Regulator of protein export for NES-containing proteins. Also plays a role in mRNA nuclear export. |
| NCBI Summary: | The protein encoded by this gene contains a nuclear transport factor 2 (NTF2) domain, which plays an important role in the trafficking of macromolecules, ions, and small molecules between the cytoplasm and nucleus. This protein may also have a role in mRNA nuclear export. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011] |
| UniProt Code: | Q9NPJ8 |
| NCBI GenInfo Identifier: | 336176110 |
| NCBI Gene ID: | 55916 |
| NCBI Accession: | NP_001229546.1 |
| UniProt Secondary Accession: | Q9NPJ8,Q0VAN8, Q5JYV5, Q5JYV6, Q5JYV7, Q9H8U0, Q9NQ64 Q9NRL7, Q9Y3M4, Q9Y3M5, D3DUY1, |
| UniProt Related Accession: | Q9NPJ8 |
| Molecular Weight: | Calculated: 12kDa; 16kDa; 21kDa; 22kDaObserved: 16kDa |
| NCBI Full Name: | NTF2-related export protein 2 isoform 2 |
| NCBI Synonym Full Names: | nuclear transport factor 2 like export factor 2 |
| NCBI Official Symbol: | NXT2�� |
| NCBI Official Synonym Symbols: | P15-2�� |
| NCBI Protein Information: | NTF2-related export protein 2 |
| UniProt Protein Name: | NTF2-related export protein 2 |
| UniProt Synonym Protein Names: | Protein p15-2 |
| Protein Family: | NTF2-related export protein |
| UniProt Gene Name: | NXT2�� |
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