Immune Checkpoint Recombinant Proteins

Human NTB-A Recombinant Protein (mFc-His Tag) (HDPT0048)

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SKU:: HDPT0048
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Human
Research Area:: Immune Checkpoint

Description
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Description

Human NTB-A Recombinant Protein (mFc-His Tag)

Description:	The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Product name:	Human NTB-A Recombinant Protein (mFc-His Tag)
Synonyms:	NTB-A,SLAMF6,Ly108,NK-T-B-antigen,CD352,KALI
Type:	protein
Size:	50 µg
Name:	NTB-A
Origin:	Human
Source:	HEK293
Protein Type:	Recombinant
Application:	Contact Technical Support
Purity:	> 95%
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C-Mouse Fc and 6×His tag
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	NTB-A（Gln22-Met226）+mFc（Pro99-Lys330）+6×His tag
Gene ID:	114836
Uniprot:	Q96DU3
Molecular Weight:	50.1 kDa

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