Immune Checkpoint Recombinant Proteins

Human NTB-A Recombinant Protein (mFc-His Tag) (HDPT0048)

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SKU:
HDPT0048
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human NTB-A Recombinant Protein (mFc-His Tag)

Description:The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Product name:Human NTB-A Recombinant Protein (mFc-His Tag)
Synonyms:NTB-A,SLAMF6,Ly108,NK-T-B-antigen,CD352,KALI
Type:protein
Size:50 µg
Name:NTB-A
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Mouse Fc and 6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:NTB-A(Gln22-Met226)+mFc(Pro99-Lys330)+6×His tag
Gene ID:114836
Uniprot:Q96DU3
Molecular Weight:50.1 kDa
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