Immune Checkpoint Recombinant Proteins
Human NTB-A Recombinant Protein (mFc-His Tag) (HDPT0048)
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- SKU:
- HDPT0048
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human NTB-A Recombinant Protein (mFc-His Tag)
| Description: | The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Product name: | Human NTB-A Recombinant Protein (mFc-His Tag) |
| Synonyms: | NTB-A,SLAMF6,Ly108,NK-T-B-antigen,CD352,KALI |
| Type: | protein |
| Size: | 50 µg |
| Name: | NTB-A |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 95% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Mouse Fc and 6×His tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | NTB-A（Gln22-Met226）+mFc（Pro99-Lys330）+6×His tag |
| Gene ID: | 114836 |
| Uniprot: | Q96DU3 |
| Molecular Weight: | 50.1 kDa |
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