Human NRCAM Recombinant Protein (RPES0813)
- SKU:
- RPES0813
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human NRCAM Recombinant Protein
Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptogenesis. It also may play a role in the molecular assembly of the nodes of Ranvier. NrCAM effects are also linked with different recognition processes and signal transduction pathways regulating cell differentiation, proliferation, or migration.
| Product Name: | Human NRCAM Recombinant Protein (RPES0813) |
| Product Code: | RPES0813 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Neuronal cell adhesion molecule, Nr-CAM, Neuronal surface protein Bravo, hBravo, gCAM-related cell adhesion molecule, Ng-CAM-related, KIAA0343, gCAM-related cell adhesion molecule |
| Accession: | Q92823-3 |
| Sequence: | Gln25-Asn600(Pro526Ala) |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human NRCAM is produced by our Mammalian expression system and the target gene encoding Gln25-Asn600(Pro526Ala) is expressed with a Fc tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 91.2 kDa |
| AP Mol Mass: | 117 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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