Human NOTCH3 ELISA Kit

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SKU:
HUFI01943
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9UM47
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
NOTCH3, CADASIL, CASILneurogenic locus notch homolog protein 3, Notch, Drosophila homolog 3, notch 3Notch homolog 3, Drosophila, Notch homolog 3
Reactivity:
Human
Research Area:
Developmental Biology

Description

Human NOTCH3 ELISA

NOTCH3 (Notch Receptor 3) is a protein that in humans is encoded by the NOTCH3 gene. It is a receptor for Notch ligands, which include Jagged1 and Jagged2. The Notch signaling pathway regulates cell-fate determination, proliferation, and differentiation in the developing embryo and plays important roles in tumor suppression and adult stem cell maintenance. Mutations in the NOTCH3 gene are associated with Alagille syndrome, a rare autosomal dominant disorder characterized by liver disease, heart defects, and other symptoms.

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