Human NHLH2 Recombinant Protein (RPPB4094)
- SKU:
- RPPB4094
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q02577
Description
| Product Name: | Human NHLH2 Recombinant Protein |
| Product Code: | RPPB4094 |
| Size: | 10µg |
| Species: | Human |
| Target: | NHLH2 |
| Synonyms: | nescient helix loop helix 2, bHLHa34, HEN2, NSCL2, Class A basic helix-loop-helix protein 34, NHLH2, KIAA0490. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | NHLH2 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 7.5), 0.2M NaCl, 50% glycerol and 5mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMMLSPDQ AADSDHPSSA HSDPESLGGT DTKVLGSVSD LEPVEEAEGD GKGGSRAALY PHPQQLSREE KRRRRRATAK YRSAHATRER IRVEAFNLAF AELRKLLPTL PPDKKLSKIE ILRLAICYIS YLNHVLDV |
Nescient Helix Loop Helix 2 (NHLH2) belongs to the basic helix-loop-helix (bHLH) transcription factor family. NHLH2 is expressed in developing and adult neuroendocrine tissues for example the pituitary and hypothalamus. NHLH2 can act as a DNA-binding protein and may be involved in the control of cell-type determination, probably in the developing nervous system.
NHLH2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 158 amino acids (1-135 a.a.) and having a molecular mass of 17.4kDa.NHLH2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | NHLH2: May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.Chromosomal Location of Human Ortholog: 1p12-p11Cellular Component: nucleus; transcription factor complexMolecular Function: protein bindingBiological Process: central nervous system development; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q02577 |
| NCBI GenInfo Identifier: | 399887 |
| NCBI Gene ID: | 4808 |
| NCBI Accession: | Q02577.1 |
| UniProt Secondary Accession: | Q02577,Q5T1P6 |
| UniProt Related Accession: | Q02577 |
| Molecular Weight: | 15,018 Da |
| NCBI Full Name: | Helix-loop-helix protein 2 |
| NCBI Synonym Full Names: | nescient helix-loop-helix 2 |
| NCBI Official Symbol: | NHLH2�� |
| NCBI Official Synonym Symbols: | HEN2; NSCL2; bHLHa34�� |
| NCBI Protein Information: | helix-loop-helix protein 2 |
| UniProt Protein Name: | Helix-loop-helix protein 2 |
| UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 34; bHLHa34; Nescient helix loop helix 2; NSCL-2 |
| Protein Family: | Helix-loop-helix protein |
| UniProt Gene Name: | NHLH2�� |
| UniProt Entry Name: | HEN2_HUMAN |
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