Neurotrophins Recombinant Proteins
Human Neurotrophin-3/NTF3 Recombinant Protein (RPES0375)
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- SKU:
- RPES0375
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Neurotrophins
Description
system_update_altDatasheet
Human Neurotrophin-3/NTF3 Recombinant Protein
Neurotrophin-3 (NT-3) is a neurotrophic factor that belongs to the NGF family and is structurally similar to beta-NGF, BDNF, and NT-4. The NT3 cDNA sequences a 257-amino acid precursor protein with a signal peptide and proprotein that are removed to generate the 119-amino acid mature NT3. The mature human, murine, and rat NT-3 amino acid sequences are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems. Human Neurotrophin-3/NTF3 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human Neurotrophin-3/NTF3 Recombinant Protein (RPES0375) |
| Product Code: | RPES0375 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3 |
| Accession: | P20783 |
| Sequence: | Tyr139-Thr 257 |
| Fusion tag: | |
| Activity: | Immobilized Human NT-3 at 10ug/ml(100 ?l/well) can bind Human TrkB-His(Cat: PKSH033579). The ED50 of Human NT-3 is 3.777 ug/ml . |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 13.6 kDa |
| AP Mol Mass: | 14 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 250mM NaCl, pH 7.2. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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