Immune Checkpoint Recombinant Proteins

Human NECTIN4 Recombinant Protein (hFc Tag) (HDPT0274)

(No reviews yet) Write a Review
SKU:
HDPT0274
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human NECTIN4 Recombinant Protein (hFc Tag)

Description:This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Product name:Human NECTIN4 Recombinant Protein (hFc Tag)
Synonyms:EDSS1; LNIR; nectin-4; PRR4; PVRL4
Type:protein
Size:50 µg
Name:NECTIN4
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:NECTIN4(Gly32-Ser349)+hFc(Glu99-Ala330)
Gene ID:
Uniprot:Q96NY8
Molecular Weight:60.5 kDa
View AllClose

0 Reviews

View AllClose