Immune Checkpoint Recombinant Proteins
Human NECTIN4 Recombinant Protein (hFc Tag) (HDPT0274)
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- SKU:
- HDPT0274
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
Description
Human NECTIN4 Recombinant Protein (hFc Tag)
| Description: | This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. |
| Product name: | Human NECTIN4 Recombinant Protein (hFc Tag) |
| Synonyms: | EDSS1; LNIR; nectin-4; PRR4; PVRL4 |
| Type: | protein |
| Size: | 50 µg |
| Name: | NECTIN4 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | Contact Technical Support |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | NECTIN4(Gly32-Ser349)+hFc(Glu99-Ala330) |
| Gene ID: | |
| Uniprot: | Q96NY8 |
| Molecular Weight: | 60.5 kDa |
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