Immune Checkpoint Recombinant Proteins

Human NECTIN4 Recombinant Protein (hFc Tag) (HDPT0274)

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SKU:: HDPT0274
UPC:
MPN:
Product Type:: Recombinant Protein
Species:: Human
Research Area:: Immune Checkpoint

Description
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Description

Human NECTIN4 Recombinant Protein (hFc Tag)

Description:	This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Product name:	Human NECTIN4 Recombinant Protein (hFc Tag)
Synonyms:	EDSS1; LNIR; nectin-4; PRR4; PVRL4
Type:	protein
Size:	50 µg
Name:	NECTIN4
Origin:	Human
Source:	HEK293
Protein Type:	Recombinant
Application:	Contact Technical Support
Purity:	Contact Technical Support
Purification:	affinity purification
Format:	Lyophilized
Conjugate:	C-Human Fc
Storage:	Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:	Research use only
Buffer:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:	Reconstitute with deionized water
Sequence:	NECTIN4(Gly32-Ser349)+hFc(Glu99-Ala330)
Gene ID:
Uniprot:	Q96NY8
Molecular Weight:	60.5 kDa