Human NBR1 ELISA Kit

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SKU:
HUFI01983
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q14596
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
NBR1, Protein 1A1-3B, Neighbor of BRCA1 gene 1 protein, Cell migRation-inducing gene 19 protein, Membrane component chromosome 17 surface marker 2
Reactivity:
Human
Research Area:
Cell Biology

Description

Human NBR1 ELISA Kit

NBR1 is in close proximity to the BRCA1 tumor suppressor gene and was originally identified as an ovarian tumor antigen. NBR1 contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. NBR1 functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. Diseases associated with NBR1 include Brooke-Spiegler Syndrome and Myofibrillar Myopathy With Early Respiratory Failure.

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