Epigenetics & Nuclear Signaling Recombinant Proteins

Human N-Glycosylase/OGG1 Recombinant Protein (RPES0472)

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SKU:
RPES0472
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Epigenetics & Nuclear Signaling

Description

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Human N-Glycosylase/OGG1 Recombinant Protein

8-oxoGuanineDNAGlycosylase/OGG1 removes 8-oxoguanine, a mutagenic base byproduct that occurs when cells are exposed to reactive oxygen. Mitochondrial targeting signal, as well as lyase action to cleave chains, is included in 8-oxoGuanine DNA Glycosylase/OGG1. Nonpapillary asbestosis, renal cell carcinoma are all conditions linked to OGG1. Deurination and cleavage of the damaged pyrimidine are two 8-oxoGuanine DNA Glycosylase/OGG1 pathways. Human N-Glycosylase/OGG1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

Product Name:Human N-Glycosylase/OGG1 Recombinant Protein (RPES0472)
Product Code:RPES0472
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:N-Glycosylase/DNA Lyase, 8-Oxoguanine DNA Glycosylase, DNA-(Apurinic or Apyrimidinic Site) Lyase, AP Lyase, OGG1, MMH, MUTM, OGH1
Accession:O15527
Sequence:Met 1-Gly345
Fusion tag:N-GST
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human N-Glycosylase is produced by our E.coli expression system and the target gene encoding Met1-Gly345 is expressed with a GST tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:65.1 kDa
AP Mol Mass:66 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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