Human MUC2 (Mucin-2) ELISA Kit

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SKU:
HUFI00773
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q02817
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
MUC2, Mucin-2, MLP, MUC-2, SMUC
Reactivity:
Human
Research Area:
Cell Biology

Description

Human MUC2 (Mucin-2) ELISA Kit

Mucin-2 is a glycoprotein that is present in the mucus layer and serves as a protective barrier. Mucins are heavily glycosylated proteins which covers epithelial cells to form an important part of the glycocalyx, or “mucous coat”. The glycocalyx helps to prevent the adhesion of pathogens to epithelial cells and also prevents the desquamation of epithelial cells from the surface. As such, Mucin-2 functions in the airway by trapping pathogens and preventing them from reaching the respiratory epithelium. It also stimulates mucus production, which helps remove allergens, bacteria, viruses, and other harmful substances from the lungs. Mucin-2 is used as a marker for diseases such as asthma, bronchiolitis obliterans syndrome (BOS), eosinophilic pneumonia, lung cancer, pulmonary sarcoidosis, cystic fibrosis (CF), pulmonary hypertension (PH), chronic obstructive pulmonary disease (COPD).

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