Neurotrophins Recombinant Proteins
Human MTPN Recombinant Protein (RPPB0775)
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- SKU:
- RPPB0775
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P58546
- Research Area:
- Neurotrophins
Description
| Product Name: | Human MTPN Recombinant Protein |
| Product Code: | RPPB0775 |
| Size: | 20µg |
| Species: | Human |
| Target: | MTPN |
| Synonyms: | Protein V-1, GCDP, Myotrophin, FLJ31098, FLJ99857. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | MTPN Human solution containing 20mM Tris-HCl pH-8 and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MCDKEFMWAL KNGDLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ |
MTPN is an ankyrin repeat protein, that stimulates protein synthesis and cardiomyocyte growth to commence cardiac hypertrophy by activating the NF-kappaB signaling cascade. Myotrophin participates in cerebellar morphogenesis and takes part in differentiation of cerebellar neurons, particularly of granule cells. High levels of MTPN are expressed in human dilated cardiomyopathic and ischemic hearts.
MTPN Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 138 amino acids (1-118 a.a.) and having a molecular mass of 15 kDa. The MTPN is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P58546 |
| NCBI GenInfo Identifier: | 21956645 |
| NCBI Gene ID: | 136319 |
| NCBI Accession: | NP_665807.1 |
| UniProt Secondary Accession: | P58546 |
| UniProt Related Accession: | P58546 |
| Molecular Weight: | 12,895 Da |
| NCBI Full Name: | myotrophin |
| NCBI Synonym Full Names: | myotrophin |
| NCBI Official Symbol: | MTPN�� |
| NCBI Official Synonym Symbols: | V-1; GCDP�� |
| NCBI Protein Information: | myotrophin; granule cell differentiation protein; protein V-1 |
| UniProt Protein Name: | Myotrophin |
| UniProt Synonym Protein Names: | Protein V-1 |
| Protein Family: | Myotrophin |
| UniProt Gene Name: | MTPN�� |
| UniProt Entry Name: | MTPN_HUMAN |
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