Human MRPS28 Recombinant Protein (RPPB4009)

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SKU:
RPPB4009
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9Y2Q9

Description

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Product Name:Human MRPS28 Recombinant Protein
Product Code:RPPB4009
Size:20µg
Species:Human
Target:MRPS28
Synonyms:Mitochondrial Ribosomal Protein S28, MRPS35, 28S Ribosomal Protein S35, Mitochondrial, MRP-S28, MRP-S35, S28mt, S35mt, 28S Ribosomal Protein S28, Mitochondrial, Mitochondrial 28S Ribosomal Protein S35, HSPC007.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:MRPS28 protein solution (0.25mg/ml) containing 20mM Phosphate buffer saline (pH 8.0), 20% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSGSPKNVE SFASMLRHSP LTQMGPAKDK LVIGRIFHIV ENDLYIDFGG KFHCVCRRPE VDGEKYQKGT RVRLRLLDLE LTSRFLGATT DTTVLEANAV LLGIQESKDS RSKEEHHEK

Mitochondrialribosomes (mitoribosomes) consist of a small 28S subunit and a large 39Ssubunit. Mitochondrial Ribosomal Protein S28, also known as MRPS28, is a proteincoding gene which encodes a 28S subunit protein which is known as mitochondrialribosomal protein S35.

MRPS28 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 139 amino acids (72-187a.a) and having a molecular mass of 15.5kDa. MRPS28 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:MRPS28: Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.
UniProt Protein Details:

Protein type:Mitochondrial; Translation; RNA-binding; Ribosomal

Chromosomal Location of Human Ortholog: 8q21.1-q21.2

Cellular Component: mitochondrion; mitochondrial small ribosomal subunit; mitochondrial inner membrane

Biological Process: mitochondrial translation; organelle organization and biogenesis

NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature. [provided by RefSeq, Jul 2008]
UniProt Code:Q9Y2Q9
NCBI GenInfo Identifier:22001973
NCBI Gene ID:28957
NCBI Accession:Q9Y2Q9.1
UniProt Secondary Accession:Q9Y2Q9,Q96Q21, B2RDZ7,
UniProt Related Accession:Q9Y2Q9
Molecular Weight:187
NCBI Full Name:28S ribosomal protein S28, mitochondrial
NCBI Synonym Full Names:mitochondrial ribosomal protein S28
NCBI Official Symbol:MRPS28��
NCBI Official Synonym Symbols:MRPS35; HSPC007; MRP-S28; MRP-S35��
NCBI Protein Information:28S ribosomal protein S28, mitochondrial; S28mt; S35mt; mitochondrial 28S ribosomal protein S35; 28S ribosomal protein S35, mitochondrial
UniProt Protein Name:28S ribosomal protein S28, mitochondrial
UniProt Synonym Protein Names:28S ribosomal protein S35, mitochondrial; MRP-S35; S35mt
Protein Family:28S ribosomal protein
UniProt Gene Name:MRPS28��
UniProt Entry Name:RT28_HUMAN
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