Human MREG Recombinant Protein (RPPB3996)
- SKU:
- RPPB3996
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8N565
Description
| Product Name: | Human MREG Recombinant Protein |
| Product Code: | RPPB3996 |
| Size: | 10µg |
| Species: | Human |
| Target: | MREG |
| Synonyms: | Melanoregulin, DSU, Dilute Suppressor Protein Homolog, WDT2,Whn-Dependent Transcript 2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | MREG protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greaterthan 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMGLRDWL RTVCCCCGCE CLEERALPEK EPLVSDNNPY SSFGATLVRDDEKNLWSMPH DVSHTEADDD RTLYNLIVIR NQQAKDSEEW QKLNYDIHTL RQVRREVRNR WKCILEDLGFQKEADSLLSV TKLSTISDSK NTRKAREMLL KLAEETNIFP TSWELSERYL FVVDRLIALD AAEEFFKLARRTYPKKPGVP CLADGQKELH YLPFPSP |
Melanoregulin(MREG) takes part in membrane fusion and in regulating the biogenesis of diskmembranes of photoreceptor rods. MREG is expressed in photoreceptor cells astwo isoforms as a result of alternative splicing. MREG interacts withPeripherin-2, a photoreceptor specific tetraspanin protein which is required topreserve normal cell structure during the renewal process of membrane fusion.Moreover, MREG plays a part in the incorporation of pigments into hair.
MREG Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) andhaving a molecular mass of 27.3kDa.MREG is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N565 |
| NCBI GenInfo Identifier: | 124487399 |
| NCBI Gene ID: | 55686 |
| NCBI Accession: | NP_060470.2 |
| UniProt Secondary Accession: | Q8N565,Q53R89, Q53TC1, Q5XKB6, Q9NWC9, Q9P1S1 |
| UniProt Related Accession: | Q8N565 |
| Molecular Weight: | 26,044 Da |
| NCBI Full Name: | melanoregulin |
| NCBI Synonym Full Names: | melanoregulin |
| NCBI Official Symbol: | MREG�� |
| NCBI Official Synonym Symbols: | DSU; WDT2�� |
| NCBI Protein Information: | melanoregulin; dilute suppressor protein homolog; whn-dependent transcript 2 |
| UniProt Protein Name: | Melanoregulin |
| UniProt Synonym Protein Names: | Dilute suppressor protein homolog |
| Protein Family: | |
| UniProt Gene Name: | MREG�� |
| UniProt Entry Name: | MREG_HUMAN |
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