](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/11936/15990/humanmouserat-cd47-monoclonal-antibody-pecyanine7-conjugated-miap410agel0674__80913__74604.1706269760.jpg?c=1&imbypass=on "Human/Mouse/Rat CD47 Monoclonal Antibody (PE/Cyanine7 Conjugated) [MIAP410](AGEL0674)")
Description
| Antibody Name: | Human/Mouse/Rat CD47 Monoclonal Antibody (PE/Cyanine7 Conjugated) |
| Antibody Code: | AGEL0674 |
| Size: | 50 Tests |
| Clone: | MIAP410 |
| Synonyms: | Leukocyte surface antigen CD47,Cd47,Integrin-associated protein,IAP |
| Host Species: | Mouse |
| Species Reactivity: | Human, Mouse, Rat |
| Applications: | FC |
| Concentration: | 5uL |
| Isotype: | IgG2a,k |
| Conjugation: | PE/Cyanine7 |
| Applications: | FC |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
| Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
| Storage: | Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. |
| Gene ID: | 961,16423,29364 |
| Uniprot: | Q08722, Q61735, P97829 |
| Background: | CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking. |
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