Cell Biology Recombinant Proteins
Human MOG Recombinant Protein (RPES4926)
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- SKU:
- RPES4926
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Biology
Description
system_update_altDatasheet
Human MOG Recombinant Protein
Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals; namely experimental autoimmune encephalomyelitis (EAE); in rodents and monkeys.
| Product Name: | Human MOG Recombinant Protein (RPES4926) |
| Product Code: | RPES4926 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Myelin-Oligodendrocyte Glycoprotein, MOG,BTN6,BTNL11,MOGIG2,NRCLP7 |
| Accession: | Q16653 |
| Sequence: | Gly30-Gly154 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our E.coli expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 15.2 kDa |
| AP Mol Mass: | 18 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM HAc-NaAc; 150mM NaCl; pH 4.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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