Enzymes Recombinant Proteins
Human MOB3B Recombinant Protein (RPPB2585)
- SKU:
- RPPB2585
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q86TA1
- Research Area:
- Enzymes
Description
Product Name: | Human MOB3B Recombinant Protein |
Product Code: | RPPB2585 |
Size: | 10µg |
Species: | Human |
Target: | MOB3B |
Synonyms: | MOB Kinase Activator 3B, Chromosome 9 Open Reading Frame 35, Monopolar Spindle 1 Binding, MOB1, Domain Containing, MOB1 Mps One Binder Kinase Activator-Like 2B, Mps One Binder Kinase Activator-Like 2B, Monopolar Spindle 1 Binding, Mob1 Homolog 2b, MOBKL2B, Domain Containing, C9orf35, MOB1D, MOB1. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile Filtered clear solution. |
Formulation: | The MOB3B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 20% glycerol. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Purity: | Greater than 90% as determined by SDS-PAGE. |
Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSIALKQ VFNKDKTFRP KRKFEPGTQR FELHKRAQAS LNSGVDLKAA VQLPSGEDQN DWVAVHVVDF FNRINLIYGT ICEFCTERTC PVMSGGPKYE YRWQDDLKYK KPTALPAPQY MNLLMDWIEV QINNEEIFPT CVGVPFPKNF LQICKKILCR LFRVFVHVYI HHFDRVIVMG AEAHVNTCYK HFYYFVTEMN LIDRKELEPL KEMTSRMCH |
MOB3B is similar to yeast Mob1 protein which binds Mps1p, a protein kinase vital for spindle pole body duplication and mitotic checkpoint regulation. MOB3B is situated on the opposite strand as the INF kappa precursor (IFNK) gene.
MOB3B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 239 amino acids (1-216) and having a molecular mass of 27.9 kDa. MOB3B is fused to a 23 amino acid His-tag at N-terminus.
UniProt Protein Function: | MOBKL2B: May regulate the activity of kinases. Belongs to the MOB1/phocein family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 9p21.2 Molecular Function:protein binding |
NCBI Summary: | The protein encoded by this gene shares similarity with the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. This gene is located on the opposite strand as the interferon kappa precursor (IFNK) gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q86TA1 |
NCBI GenInfo Identifier: | 56749334 |
NCBI Gene ID: | 79817 |
NCBI Accession: | Q86TA1.2 |
UniProt Secondary Accession: | Q86TA1,Q8NEB4, Q9H8V4, |
UniProt Related Accession: | Q86TA1 |
Molecular Weight: | 25,464 Da |
NCBI Full Name: | MOB kinase activator 3B |
NCBI Synonym Full Names: | MOB kinase activator 3B |
NCBI Official Symbol: | MOB3B�� |
NCBI Official Synonym Symbols: | MOB1D; C9orf35; MOBKL2B�� |
NCBI Protein Information: | MOB kinase activator 3B |
UniProt Protein Name: | MOB kinase activator 3B |
UniProt Synonym Protein Names: | Mob1 homolog 2b; Mps one binder kinase activator-like 2B |
Protein Family: | MOB kinase activator |
UniProt Gene Name: | MOB3B�� |
UniProt Entry Name: | MOB3B_HUMAN |