Human MMP11 ELISA Kit

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SKU:
HUFI00567
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P24347
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
MMP-11, Matrix Metalloproteinase 11, MMP11, SL-3, ST3, STMY3, Stromelysin-3, stromelysin 3, stromelysin III
Reactivity:
Human
Research Area:
Cell Biology

Description

Human MMP11 ELISA

Human MMP11 (matrix metalloproteinase-11) is involved in the extracellular matrix breakdown that occurs in normal physiological processes, such as embryonic development, reproduction, and tissue remodelling, as well as diseasem like arthritis and metastasis. Intracellular activation of MMP11 is promoted by furin in the constitutively secretory pathway. This enzyme cuts alpha 1-proteinase inhibitor but only slightly damages extracellular matrix structural proteins in contrast to other MMPs. MMP11 is involved with the pathogenesis of several diseases, including dermatofibrosarcoma protuberans and cutaneous fibrous histiocytoma. Matrix metalloproteinases and extracellular matrix degradation are two pathways influenced by it.

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