Human MMP-9 Recombinant Protein (His tag)

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SKU:
RPES6045
Product Type:
Recombinant Protein
Species:
Human

Description

Product Name:Human MMP-9 Recombinant Protein (His tag)
Product Code:RPES6045
Size:20µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:Matrix metalloproteinase-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, MMP9, CLG4B, GELB, MANDP2
Mol Mass:77.66 kDa
AP Mol Mass:85 kDa
Tag:C-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Met 1-Asp 707
Accession:P14780
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein; which is produced by normal alveolar macrophages and granulocytes; can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4; SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; angiogenesis; bone development; wound healing; cell migration; learning and memory; as well as in pathological processes; such as arthritis; intracerebral hemorrhage; and metastasis.
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