Immune Checkpoint Recombinant Proteins

Human MICA Recombinant Protein (His Tag) (HDPT0142)

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SKU:
HDPT0142
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human MICA Recombinant Protein (His Tag)

Description:This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Product name:Human MICA Recombinant Protein (His Tag)
Synonyms:MIC-A, PERB11.1
Type:protein
Size:50 µg
Name:MICA
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 95%
Purification:affinity purification
Format:Lyophilized
Conjugate:C-6×His tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:MICA （Glu24-Trp307）+6×His tag
Gene ID:100507436
Uniprot:Q29983
Molecular Weight:55-70 kDa
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