Enzymes Recombinant Proteins

Human METTL21A Recombinant Protein (RPPB1940)

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SKU:
RPPB1940
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q8WXB1
Research Area:
Enzymes

Description

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Product Name:Human METTL21A Recombinant Protein
Product Code:RPPB1940
Size:10µg
Species:Human
Target:METTL21A
Synonyms:Protein N-lysine methyltransferase METTL21A, HSPA lysine methyltransferase, HSPA-KMT, Hepatocellular carcinoma-associated antigen 557b, Methyltransferase-like protein 21A, METTL21A, FAM119A, HCA557B, Methyltransferase Like 21A.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:The METTL21A solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 30% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSTDRKVAL EFLKSNVQAN LPPHIQTKTV VKELTWGQNL GSFSPGEFDL ILGADIIYLE ETFTDLLQTL EHLCSNHSVI LLACRIRYER DNNFLAMLER QFTVRKVHYD PEKDVHIYEA QKRNQKEDL

METTL21A, which is a part of the methyltransferase superfamily, is a Protein-lysine methyltransferase that in vitro methylates HSPA1, HSPA5 and HSPA8.

METTL21A Human Recombinant produced in E. coli is a single polypeptide chain containing 149 amino acids (93-218) and having a molecular mass of 17 kDa.METTL21A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:FAM119A: a methyltransferase of the METTL21 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; EC 2.1.1.-; Methyltransferase, protein lysineChromosomal Location of Human Ortholog: 2q33.3Cellular Component: cytoplasmMolecular Function: protein binding; protein-lysine N-methyltransferase activity; Hsp70 protein binding; ATPase bindingBiological Process: regulation of ATPase activity; protein amino acid methylation; peptidyl-lysine methylation
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8WXB1
NCBI GenInfo Identifier:14495701
NCBI Gene ID:151194
NCBI Accession:AAH09462.1
UniProt Secondary Accession:Q8WXB1,Q53RV0, Q8N1Z9, Q96GH6
UniProt Related Accession:Q8WXB1
Molecular Weight:
NCBI Full Name:FAM119A protein
NCBI Synonym Full Names:methyltransferase like 21A
NCBI Official Symbol:METTL21A��
NCBI Official Synonym Symbols:FAM119A; HCA557b; HSPA-KMT��
NCBI Protein Information:protein N-lysine methyltransferase METTL21A; HSPA lysine methyltransferase; family with sequence similarity 119, member A; heat shock protein 70kDa lysine (K) methyltransferase; hepatocellular carcinoma-associated antigen 557b; methyltransferase-like protein 21A; protein-lysine methyltransferase METTL21A
UniProt Protein Name:Protein N-lysine methyltransferase METTL21A
UniProt Synonym Protein Names:HSPA lysine methyltransferase; HSPA-KMT; Hepatocellular carcinoma-associated antigen 557b; Methyltransferase-like protein 21A
Protein Family:
UniProt Gene Name:METTL21A��
UniProt Entry Name:MT21A_HUMAN
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