Human METAP1 Recombinant Protein (RPES0959)
- SKU:
- RPES0959
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human METAP1 Recombinant Protein
Methionine Aminopeptidase 1 is a member of the M24 family of metalloproteases. METAP1 is a core component of the G(2)/M transition that occurs during the cell cycle and may be a useful target for the development of new anticancer drugs. METAP1 and METAP2 have dissimilar substrate preferences owing to the varying sizes and shapes of the active sites. N-terminal methionine removal is catalysed by a group of enzymes known as methionine aminopeptidases (MetAPs), which are required for cell development. Inhibition of METAPs provides a novel strategy in developing anti-cancer drugs. Human METAP1 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human METAP1 Recombinant Protein (RPES0959) |
| Product Code: | RPES0959 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Methionine aminopeptidase 1, MAP 1, MetAP 1, Peptidase M 1, METAP1,MAP1A,MetAP1A |
| Accession: | P53582 |
| Sequence: | Met1-Phe386 |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human METAP1 is produced by our E.coli expression system and the target gene encoding Met1-Phe386 is expressed. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 43.2 kDa |
| AP Mol Mass: | 38&45-50 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM Tris,500mM NaCl,10%glycerol,pH8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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