Description
| Product Name: | Human MeCP2 Recombinant Protein (His tag) | 
| Product Code: | RPES6610 | 
| Size: | 20µg | 
| Species: | Human | 
| Expression Host: | E.coli | 
| Synonyms: | MeCp-2 protein | 
| Mol Mass: | 19 kDa | 
| AP Mol Mass: | 32 kDa | 
| Tag: | N-His | 
| Purity: | > 95 % as determined by reducing SDS-PAGE. | 
| Endotoxin Level: | Please contact us for more information. | 
| Bio Activity: | Testing in progress | 
| Sequence: | Met1-Lys177 | 
| Accession: | P51608 | 
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. | 
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. | 
| Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. | 
| Reconstitution: | Please refer to the printed manual for detailed information. | 
| Background: | Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). | 
 
 
             
             
             
             
            