Human MBIP Recombinant Protein (RPES4329)

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SKU:
RPES4329
Product Type:
Recombinant Protein
Species:
Human

Description

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Human MBIP Recombinant Protein

MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It’s function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.

Product Name:Human MBIP Recombinant Protein (RPES4329)
Product Code:RPES4329
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:MAP3K12-Binding Inhibitory Protein 1, MAPK Upstream Kinase-Binding Inhibitory Protein, MUK-Binding Inhibitory Protein, MBIP
Accession:Q9NS73
Sequence:Met 1-Pro344
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human MAP3K12-Binding Inhibitory Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Pro344 is expressed with a 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:42.5 kDa
AP Mol Mass:50 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM Tris, pH8.0.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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