Immune Checkpoint Recombinant Proteins

Human MASP2 Recombinant Protein (hFc Tag) (HDPT0172)

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SKU:
HDPT0172
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immune Checkpoint

Description

Human MASP2 Recombinant Protein (hFc Tag)

Description:This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Product name:Human MASP2 Recombinant Protein (hFc Tag)
Synonyms:MAP19, MASP-2, MASP1P1, sMAP
Type:protein
Size:50 µg
Name:MASP2
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:> 90%
Purification:affinity purification
Format:Lyophilized
Conjugate:N-Human Fc tag
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:hFc(Glu99-Ala330)+MASP2 (Gln298-Ser684)
Gene ID:10747
Uniprot:O00187
Molecular Weight:68.4 kDa
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