Human MAP4K1 (MEK Kinase Kinase 1) ELISA Kit (HUFI07696)

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SKU:
HUFI07696
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q92918
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
HPK1, MAP4K1, MEK kinase kinase 1, MEKKK 1
Reactivity:
Human

Description

Human MAP4K1 (MEK Kinase Kinase 1) ELISA

MAP4K1 (MEK Kinase Kinase 1) is a serine/threonine protein kinase that activates MAPK8 (JNK1), which in turn activates signalling pathways and induces apoptosis. MAP4K1 (MEK Kinase Kinase 1) has been found to be important for correct chromosome segregation during mitosis, and necessary for the mitotic spindle formation, upon mitogenic stimulation by platelet derived growth factor receptor (PDGFRA). Diseases associated with MAP4K1 (MEK Kinase Kinase 1) include some forms of cancer, especially tumors originating from hematopoietic origin such as diffuse large B-cell lymphoma.

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