Metabolism Recombinant Proteins

Human MAA/GSTZ1 Recombinant Protein (RPES4159)

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SKU:
RPES4159
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism

Description

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Human MAA/GSTZ1 Recombinant Protein

Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation with glutathione, for example, mutagens, carcinogens and several therapeutic drugs. MAAI is a bifunctional protein with low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. MAAI can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. But it has minimal glutathione-conjugating activity with 7-chloro-4-nitrobenz-2-oxa-1, ethacrynic acid 3-diazole and maleylacetoacetate isomerase activity.

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