Signal Transduction Recombinant Proteins
Human LYVE1/HAR Recombinant Protein (RPES3998)
- SKU:
- RPES3998
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Signal Transduction
Description
Human LYVE1/HAR Recombinant Protein
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
| Product Name: | Human LYVE1/HAR Recombinant Protein (RPES3998) |
| Product Code: | RPES3998 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, LYVE-1, Cell Surface Retention Sequence-Binding Protein 1, CRSBP-1, Extracellular Link Domain-Containing Protein 1, Hyaluronic Acid Receptor, LYVE1, CRSBP1, HAR, XLKD1 |
| Accession: | Q9Y5Y7 |
| Sequence: | Leu20-Thr 238 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Thr238 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 24.6 kDa |
| AP Mol Mass: | 46 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM Tris-Citrate,1 50mM NaCl, pH 7.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Related Products
Human LYVE1 Recombinant Protein (RPPB2561)
Enzymes Recombinant Proteins
Mouse LYVE1/HAR Recombinant Protein (RPES0564)
Signal Transduction Recombinant Proteins
Human LYVE1 25-235 a.a. Recombinant Protein (RPPB2560)
Enzymes Recombinant Proteins
Human HARS Recombinant Protein (RPPB1796)
Enzymes Recombinant Proteins
Human HARS Recombinant Protein (RPPB1797)
Enzymes Recombinant Proteins
Human HARS Recombinant Protein (RPPB1798)
Enzymes Recombinant Proteins
Mouse LYVE1 Sf9 Recombinant Protein (RPPB2562)
Enzymes Recombinant Proteins
Human RNAS2 Recombinant Protein
Human TGFB1 Recombinant Recombinant Protein (RPPB0968)
Growth Factors & Cytokines Recombinant Proteins